Inhibitor of Apoptosis (IAP) proteins in pediatric leukemia: Molecular pathways and novel approaches to therapy
Inhibitor of Apoptosis (IAP) proteins are a family 14765-prb-a01 of proteins with antiapoptotic functions that contribute to the evasion of apoptosis, a form of programmed cell death.IAP proteins are expressed at high levels in a variety of human cancers including childhood acute leukemia.This elevated expression has been associated with unfavorabl